Purchase Anandamide (AEA) (94421-68-8) Producers – Phcoker

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Purchase Anandamide (AEA) (94421-68-8) Producers – Phcoker

Anandamide (AEA) (94421-68-8) Specs

Product Title
Anandamide (AEA)

Chemical Title
Arachidonylethanolamide;N-Arachidonoylethanolamine;Anandamide (20.4, n-6);

N-Arachidonoyl-2-hydroxyethylamide;Arachidonoyl ethanolamide;AEA;

CAS Quantity
94421-68-8

InChIKey
LGEQQWMQCRIYKG-DOFZRALJSA-N

SMILE
CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCO

Molecular System
C22H37NO2

Molecular Weight
347.53

Monoisotopic Mass
347.282429 g/mol

Melting Level
N/A

Boiling Level
522.3±50.0 °C(Predicted)

Density
0.92 g/mL at 25 °C(lit.)

Shade
mild yellow

Storage temp
−20°C

Solubility
ethanol: soluble

Software
It’s used for reminiscence, motivation, cognitive processes, movement management, ache management, urge for food stimulation and fertility.

 
What’s Anandamide (AEA)?
Anandamide, also called N-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid. It has a construction similar to that of tetrahydrocannabinol, the energetic constituent of hashish. It’s degraded primarily by the fatty acid amide hydrolase (FAAH) enzyme, which converts anandamide into ethanolamine and arachidonic acid, Lastly, Anandamide is synthesized in neuron by a condensation response happens between arachidonic acid and ethanolamine below the regulation of calcium ion and cyclic monophosphate adenosidase. It’s a precursor of a bunch of physiologically energetic substances (Prostamides) that play a job in lots of bodily actions, together with urge for food, reminiscence, ache, despair, and fertility. As well as, Anandamide additionally inhibits people Proliferation of breast most cancers cells.

Anandamide exists in lots of organisms, corresponding to sea urchin roe, pigs’ brains and mice livers, and so forth, however its quantity is small. Additionally, researchers additionally discovered Anandamide and two substances (N-oleoylethanolamine and N-Linoleylethanolamine) in darkish chocolate. Anandamide even exists in some Processed grains, (white bread), Alcohol (particularly, continual use or binge consuming), Refined sugar, Trans fat, Meals fried in vegetable oil and Non-organic meals that comprise pesticides and so forth.

As a part of the endocannabinoid system (ECS), Anandamide is classed as a regulator of homeostasis together with one other class of cannabis-like chemical 2-AG and endogenous cannabinoid receptors all through the physique. This method exists In all vertebrates. Anandamide performs a job in regulating feeding habits and neurogenic motivation and pleasure, protecting our physique and thoughts in stability. Research have discovered that our feelings, happiness, concern, nervousness, and talent to resist stress are all regulated by the endocannabinoid system, and numerous ailments from schizophrenia to despair are accompanied by irregular anandamide ranges.

Anandamide, just like THC, is a partial agonist of CB1R. It might trigger potential enhancements by “full” activation of the mind system. It’s price noting that every one these results of Anandamide appear to be enhanced by pharmacologically inhibiting its metabolic degradation. Anandamide’s discovery might result in the event of a wholly new household of therapeutic medication.

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